LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]LGR5小鼠单克隆抗体[克隆ID：OTI2A2]

产品中心 > OriGene > LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]LGR5小鼠单克隆抗体[克隆ID：OTI2A2]

LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]LGR5小鼠单克隆抗体[克隆ID：OTI2A2]

LGR5小鼠单克隆抗体，克隆OTI2A2
TA503316S， 30ul
TA503316， 100ul
品牌：origene

价格：￥0.00

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Product Data
Clone Name	OTI2A2
Applications	FC, IF, IHC, IP, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100, IP 2ug/500ul
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in HEK293T Cell.
Isotype	IgG1
Formulation	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	99.8 kDa
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

The use of this Antibodies has been cited in the following citations:
Engineering a Bioartificial Human Colon Model Through Decellularization and Recellularization ,Chen, HJ;Shuler, ML;, Methods Mol. Biol. 2019 ,PubMed ID 30542993 [LGR5]
Selection of a Malignant Subpopulation from a Colorectal Cancer Cell Line ,Lai, PL;Chen, TC;Feng, CY;Lin, H;Wu, N;Chen, Y;, bioRxiv 2019 [LGR5]
Acute exposure to deoxynivalenol inhibits porcine enteroid activity via suppression of the Wnt/β-catenin pathway ,Li, XG;Zhu, M;Chen, MX;Fan, HB;Fu, HL;Zhou, JY;, Toxicology Letters 2019 ,PubMed ID 30690062 [LGR5]
Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri ,Liu, S;Zheng, Z;Ji, S;Liu, T;Hou, Y;Li, S;Li, G;, Fish Shellfish Immunol. 2018 ,PubMed ID 29908321 [LGR5]
NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells ,Ma, X;Wang, B;Wang, X;Luo, Y;Fan, W;, PLoS ONE 2018 ,PubMed ID 29689047 [LGR5]
Liver damage, proliferation, and progenitor cell markers in experimental necrotizing enterocolitis ,Miyake, H;Li, B;Lee, C;Koike, Y;Chen, Y;Seo, S;Pierro, A;, J. Pediatr. Surg. 2018 ,PubMed ID 29502797 [LGR5]
Identification of PMN-released Mutagenic Factors in a Co-culture Model for Colitis-associated Cancer ,Granofszky, N;Lang, M;Khare, V;Schmid, G;Scharl, T;Ferk, F;Jimenez, K;Knasmüller, S;Campregher, C;Gasche, C;, Carcinogenesis 2017 ,PubMed ID 29106440 [LGR5]
Immuno-proteomic discovery of tumor tissue autoantigens identifies olfactomedin 4, CD11b, and integrin alpha-2 as markers of colorectal cancer with liver metastases ,Yang, Q;Bavi, P;Wang, JY;Roehrl, MH;, J Proteomics 2017 ,PubMed ID 28669815 [LGR5]
LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1 ,Wang, B;Chen, Q;Cao, Y;Ma, X;Yin, C;Jia, Y;Zang, A;Fan, W;, PLoS ONE 2016 ,PubMed ID 28033430 [LGR5]
Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase ,Patel, NJ;Sharon, C;Baranwal, S;Boothello, RS;Desai, UR;Patel, BB;, Oncotarget 2016 ,PubMed ID 27705927 [LGR5]
A recellularized human colon model identifies cancer driver genes ,Chen, HJ;Wei, Z;Sun, J;Bhattacharya, A;Savage, DJ;Serda, R;Mackeyev, Y;Curley, SA;Bu, P;Wang, L;Chen, S;Cohen-Gould, L;Huang, E;Shen, X;Lipkin, SM;Copeland, NG;Jenkins, NA;Shuler, ML;, Nat. Biotechnol. 2016 ,PubMed ID 27398792 [LGR5]
Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer ,Osawa, H;Takahashi, H;Nishimura, J;Ohta, K;Haraguchi, N;Hata, T;Yamamoto, H;Mizushima, T;Takemasa, I;Doki, Y;Mori, M;, Br. J. Cancer May 2016 ,PubMed ID 27140312 [LGR5]
LGR5 activates non-canonical Wnt-signaling and inhibits aldosterone production in the human adrenal ,Shaikh, LH;Zhou, J;Teo, AE;Garg, S;Neogi, SG;Figg, N;Yeo, GS;Yu, H;Maguire, JJ;Zhao, W;Bennett, MR;Azizan, EA;Davenport, AP;McKenzie, G;Brown, MJ;, J. Clin. Endocrinol. Metab. Apr 2015 ,PubMed ID 25915569 [LGR5]
CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression ,Hsu, HC;Liu, YS;Tseng, KC;Yang, TS;Yeh, CY;You, JF;Hung, HY;Chen, SJ;Chen, HC;, J. Cancer Res. Clin. Oncol. July 2014 ,PubMed ID 25060070 [LGR5]
LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/ß-catenin signaling pathway in colorectal cancer cells ,Hsu, HC;Liu, YS;Tseng, KC;Tan, BC;Chen, SJ;Chen, HC;, Cell. Signal. July 2014 ,PubMed ID 25025569 [LGR5]
Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro ,Wang, J;Guo, X;Lui, M;Chu, PJ;Yoo, J;Chang, M;Yen, Y;, PLoS ONE, Jan 2014. ,PubMed ID 24465489 [LGR5]
Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis ,Jiang, N;Zhou, J;Chen, M;Schiff, MD;Lee, CH;Kong, K;Embree, MC;Zhou, Y;Mao, JJ;, Biomaterials Dec 2013. ,PubMed ID 24345734 [Lgr5]
Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers ,Chen Wu, Yuanyuan Xie, Feng Gao, Yanan Wang, Yawei Guo, Huanna Tian, Yanshuang Li, Wufang Fan, Gene. 2013 Aug 1;525(1):18-25 ,PubMed ID 23664892 [LGR5]
PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages ,Pastò A, Marchesi M, Diamantini A, Frasson C, Curtarello M, Lago C, Pilotto G, Parenti AR, Esposito G, Agostini M, Nitti D, Amadori A, PLoS One. 2012;7(8):e43379 ,PubMed ID 22927961 [LGR5]