bioGenous™ 小鼠小肠类器官培养试剂盒是一种专为成年小鼠肠干细胞来源的肠道类器官设计的无血清培养基。在该完全培养基中培养的类器官主要由以下细胞组成：肠道干细胞（LGR5+）、快速增殖细胞（KI67+）、吸收性肠上皮细胞（ALPI+）、潘氏细胞（ATOH1+）和杯状细胞（MUC2+）。这些小鼠肠道类器官能够高度重现体内肠道上皮的自我更新能力、组织结构、细胞类型组成及功能特性，因此是研究肠道稳态与疾病机制的理想体外模型。

Product Description

bioGenous™ Mouse Intestinal Organoid Kit is a serum-free culture medium designed for mouse intestinal organoids derived from adult intestinal stem cells. Organoids grown in this complete medium predominantly consist of intestine stem cells (LGR5+), rapidly proliferating cells (KI67+), absorptive enterocytes (ALPI+), Paneth cells (ATOH1+), and goblet cells (MUC2+). These mouse intestinal organoids faithfully recapitulate the characteristics of in vivo intestinal epithelium in terms of self-renewal capacity, tissue architecture, cell type composition, and functionality. Therefore, they serve as an ideal in vitro model for studying intestinal homeostasis and disease mechanisms.