Product Description

bioGenous™ Mouse Intestinal Organoid Kit Plus is a comprehensive system designed for the generation and maintenance of mouse intestinal organoids derived from adult stem cells. This kit provides a complete set of reagents for isolating crypts from the intestine, recovering crypts, analyzing crypt activity, and culturing organoids. This kit effectively preserves crypt activity and enhances the formation rate of intestine organoids. The mouse intestinal organoids consist of intestine stem cells (LGR5+), rapidly proliferating cells (Ki67+), absorptive enterocytes (ALPI+), Paneth cells (Atoh1+), and goblet cells (MUC2+). These organoids faithfully recapitulate the features of the in vivo intestinal epithelium in terms of self-renewal capacity, tissue structure, cell types, and function, making them an ideal in vitro model for studying intestinal homeostasis and disease mechanisms.