<C152121> 伯桢生物(bioGenous) SB202190 (FHPI)

栏目：生长因子及小分子（用于类器官培养）
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SB202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[1][2]. SB202190 induces autophagy[3].

SB202190 (FHPI)


          产品编号       

产品名称

         包装规格        

        价格       

C152121   

      SB202190 (FHPI)     

50mg

1440


产品介绍

Background

SB202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits. SB202190 induces autophagy.

M. W t

331.34

Formula

C20H14FN3O

CAS No

152121-30-7

Storage

Powder

- 20°C

3 years

4°C

2 year C20H14FN3O

In solvent

-80°C

6 months                                     

-20°C 

1 month

Solubility

DMSO

100 mg/mL(301.80 mM; Need ultrasonic)

Ethanol

12 mg/mL(36.22 mM)

H2O

< 0.1 mg/mL(insoluble)

 


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