<C252917> 伯桢生物(bioGenous) CHIR-99021

栏目：生长因子及小分子（用于类器官培养）
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CHIR-99021 is a potent and selective GSK-3α/β inhibitor with IC₅₀s of 10 nM and 6.7 nM. Laduviglusb shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusb is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusb enhances mouse and human embryonic stem cells self-renewal. Laduviglusb induces autophagy.


CHIR-99021

     产品编号      

       产品名称       

     包装规格    

     价格    

C252917   

CHIR-99021

10mg

1584



产品介绍

Background

CHIR-99021 is a potent and selective GSK-3α/β inhibitor with IC₅₀s of 10 nM and 6.7 nM. Laduviglusb shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusb is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusb enhances mouse and human embryonic stem cells self-renewal. Laduviglusb induces autophagy.

Alias

Laduviglusb; CT99021

M. W t

465.34

Formula

C₂₃H₁₉C₂N₆

CAS No

252917-06-9

Storage

- Powder: -20 °C, 3 years
- 4 °C, 2 years
- In solvent: -80 °C, 6 months
- -20 °C, 1 month

Solubility

- DMSO: 16.67 mg/mL (35.82 mM)
- H₂O: < 0.1 mg/mL (insoluble)


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