<C629401> 伯桢生物(bioGenous) Y-27632 dihydrochloride

栏目：生长因子及小分子（用于类器官培养）
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Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hiPSCs) to selectively differentiate towards mesodermal lineage via epithelial-mesenchymal transition-like modulation.


Y-27632 dihydrochloride

         产品编号         

产品名称

     包装规格     

      价格      

C629401   

     Y-27632 dihydrochloride     

100mg

4219.5


产品介绍

Background

Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hiPSCs) to selectively differentiate towards mesodermal lineage via epithelial-mesenchymal transition-like modulation.

M. W t

320.26

Formula

C₁₄H₂₃Cl₂N₂O

CAS No

129830-38-2

Storage

- Powder: -20 °C, 3 years
- In solvent: -80 °C, 6 months
- -20 °C, 1 month

Solubility

- DMSO: 33.33 mg/mL (104.07 mM; Need ultrasonic)
- H₂O: 100 mg/mL (312.25 mM; Need ultrasonic)


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